What are the opening hours?

Monday 11am - 10pm Tuesday 11am - 10pm Wednesday 11am - 10pm Thursday 11am - 10pm Friday 11am - 10pm Saturday 11am - 10pm Sunday 11am - 10pm

Five Guys

Name: Five Guys
Address: 5331 S. Calle Santa Cruz, #125, Tucson, AZ, 85706, US
Telephone: +15202941354
Price range: $

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Your nearby Five Guys at 5331 S. Calle Santa Cruz in Tucson is ready to offer you a classic take on burgers, hot dogs, fries, milkshakes and more!

Whether it's using fresh ground beef (there are no freezers in our restaurants), double-cooking our fries in 100 percent peanut oil, hand-preparing fresh ingredients every morning or serving peanuts while you wait, we strive to provide the best experience each and every time you visit. With more than 250,000 ways to customize your burger and 1,000+ milkshake combinations, satisfying your craving is just a click away!

10/30/2026

Technique is everything during the Five Guys Games. Watch your favorite contestants race against the clock in On the Line: The World Burger Games. Available on .

10/29/2026

Who's getting fries today?

10/19/2026

If you could only pick one...

10/16/2026

Collect limited edition ‘On The Line: The World Burger Games’ cards with any purchase. In store only while supplies last.

Our newest documentary series, On the Line: The World Burger Games is now available on Prime Video.

10/16/2026

Burgers, drama, glory. The new docuseries ‘On The Line: The World Burger Games’ has everything. Extra everything. At no extra charge. Available on .

10/15/2026

Eight Five Guys crew members. One stage. $100,000 on the line. On the Line: The World Burger Games streams tomorrow, October 16.

The Five Guys Games takes what our crews do every shift and puts it under arena lights. Same cheese. Same foil. Same standard.

Across five episodes, On the Line follows eight finalists from their home stores all the way to the finals stage.

10/11/2026

Keep your eyes on the fries. Watch our crew members compete in ‘On the Line: The World Burger Games’. Streaming October 16th.

10/11/2026

Watch our crew members compete in ‘On the Line: The World Burger Games’. Streaming October 16th. The pressure is stacking up.

10/09/2026

Watch our crew members compete in ‘On the Line: The World Burger Games’. Streaming October 16th. Who will be crowned burger champ?

10/07/2026

The jury’s out. Does mustard belong on burgers? 🧑‍⚖️

10/01/2026

Today’s the day to turn your coworker into a real friend! ☕🥤❤️

09/28/2026

No place we'd rather be 😍🍔

Address

5331 S. Calle Santa Cruz, #125
Tucson, AZ
85706

Opening Hours

Monday	11am - 10pm
Tuesday	11am - 10pm
Wednesday	11am - 10pm
Thursday	11am - 10pm
Friday	11am - 10pm
Saturday	11am - 10pm
Sunday	11am - 10pm

Telephone

+15202941354

Website

https://restaurants.fiveguys.com/5331-s-calle-santa-cruz

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