Main Street Grille

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Main Street Grille Formerly a five and dime store turn into a neighborhood bar and grille!! American food and great atm
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10/27/2026

🔥 TUESDAY NIGHT SPECIALS AT MAIN STREET GRILLE! 🔥

It’s WING NIGHT, and we’ve got some delicious specials lined up for you tonight!

🍗 WING NIGHT! – Come enjoy your favorite wings, tossed in one of our delicious sauces! Dine-in only!

🧀 Chicken Cordon Bleu – A delicious dinner favorite featuring tender chicken, ham, and melted Swiss cheese!

🍝 LIMITED ALFREDO! – Get it while it lasts! Rich, creamy Alfredo pasta that’s sure to hit the spot!

APPETIZERS

🧀 Fried Cheese Curds – Golden, crispy, and loaded with cheesy goodness!

🍄 Stuffed Mushrooms – Stuffed with chicken, cream cheese, and spinach, topped with our homemade hollandaise sauce!

🍽️ Come hungry and bring your appetite! We’ve got something for everyone tonight!

📍 Main Street Grille – Historic Downtown Walterboro

Great food, great atmosphere, and a great Tuesday night!

10/21/2026

🍽️ WEDNESDAY NIGHT SPECIALS AT MAIN STREET GRILLE! 🍽️

Come hungry tonight! We’ve got some delicious Southern favorites and homemade specialties waiting for you!

🔥 APPETIZERS

🧀 Wisconsin Cheese Curds – Golden, crispy, and delicious!

🍄 Stuffed Mushrooms – Stuffed with chicken, spinach, and cream cheese, then topped with our homemade hollandaise sauce!

🍤 TONIGHT’S ENTRÉES

🍤 Famous Colleton Shrimp & Grits – Our signature dish featuring stone-ground grits with spinach, tomatoes, bacon, and cheese, smothered in our rich Parmesan cream sauce! Choose your grits sautéed or fried!

🍝 Chicken Alfredo – Tender chicken served over pasta tossed in a rich, creamy Alfredo sauce!

🍝 Shrimp Alfredo – Succulent shrimp served over pasta with our delicious creamy Alfredo sauce!

🍴 Great food, great atmosphere, and hometown hospitality!

Come spend your Wednesday evening with us at Main Street Grille in historic downtown Walterboro!

🍷 Doors open at 4 PM!

We look forward to seeing you tonight!

Come see us tonight at Main Street Grille!! 🍻 🍔 🤩
10/21/2026

Come see us tonight at Main Street Grille!! 🍻 🍔 🤩

10/20/2026

🔥🍽️ TUESDAY NIGHT SPECIALS AT MAIN STREET GRILLE! 🍽️🔥

We’ve got an incredible lineup of delicious specials tonight! Come hungry and let us take care of dinner!

🍄 APPETIZER SPECIAL

Stuffed Mushrooms – Delicious mushrooms stuffed with a savory, creamy filling of spinach and chicken and drizzled with our homemade hollandaise sauce!

🍗 IT’S WING NIGHT! 🍗

Wing Night is back with FOUR NEW FLAVORS you don’t want to miss!

🔥 Spicy Peach – Sweet with a little kick!

🍒 Cherry Cola – A delicious combination of sweet and savory!

🌶️ Chili Lime – Zesty, tangy, and packed with flavor!

🍎 Smoky Applewood – Rich, smoky flavor with a touch of sweetness!

Wing Night is DINE-IN ONLY!

🥩🍤 TONIGHT’S DINNER SPECIALS

🍝 Chicken or Shrimp Alfredo – Your choice of tender chicken or succulent shrimp tossed in our rich, creamy Alfredo sauce over pasta!

🥩 Black and Tan Ribeye – A juicy, flavorful ribeye seasoned with our signature blackening spices and cooked to perfection!

🦪 Surf & Turf – The best of both worlds! Enjoy a delicious steak paired with your choice of shrimp, scallops, or oysters!

🐟 Honey Garlic Salmon – A perfectly grilled salmon fillet finished with our delicious honey garlic sauce. A fantastic combination of sweet and savory!

🍻 Great Food, Cold Drinks & Good Company!

Skip cooking tonight and come enjoy a great meal with us at Main Street Grille in Historic Downtown Walterboro!

🔥 Come hungry, bring your friends, and let us handle dinner!

🍤🔥 WEDNESDAY NIGHT SPECIALS AT MAIN STREET GRILLE! 🔥🍤We’ve got an incredible lineup of delicious appetizers and mouthwat...
10/14/2026

🍤🔥 WEDNESDAY NIGHT SPECIALS AT MAIN STREET GRILLE! 🔥🍤

We’ve got an incredible lineup of delicious appetizers and mouthwatering entrées tonight! Come hungry and let us take care of dinner! 🍽️

🥘 TONIGHT’S APPETIZERS

🧀 Wisconsin Cheese Curds – Golden, crispy, and fried to perfection! A Main Street favorite!

🍄 Chicken & Spinach Stuffed Mushrooms – Tender mushroom caps stuffed with a savory blend of chicken, cream cheese, and spinach, then topped with our rich, homemade hollandaise sauce. Absolutely delicious!

🔥 Buffalo Chicken & Spinach Dip – A creamy, cheesy combination of buffalo chicken and spinach, served piping hot with crispy tortilla chips. Perfect for sharing!

🍽️ TONIGHT’S ENTRÉES

🍤 Our Famous Colleton Shrimp & Grits – A Lowcountry favorite! Delicious shrimp smothered in our signature white Parmesan cream sauce, served over stone-ground grits loaded with spinach, tomatoes, cheese, and bacon. Choose your grits sautéed or fried! Southern comfort food at its finest!

🐟 Honey Habanero Grilled Salmon – A beautiful salmon fillet seasoned with our signature honey habanero seasoning, grilled to perfection, and drizzled with our homemade honey habanero sauce. The perfect balance of sweet and heat! Served with your choice of one side and a side salad.

🍹 Make your Wednesday night a delicious one! Whether you’re craving fresh seafood, Southern comfort food, or just a few great appetizers, we’ve got something special waiting for you!

📍 Main Street Grille | Historic Downtown Walterboro

🕓 Doors open at 4 PM!

Great food. Great atmosphere. Always a good time at Main Street Grille!

🔥 IT’S WING NIGHT AT MAIN STREET GRILLE! 🔥Tuesday night just got a whole lot tastier! Come hungry because we’ve got some...
10/13/2026

🔥 IT’S WING NIGHT AT MAIN STREET GRILLE! 🔥

Tuesday night just got a whole lot tastier! Come hungry because we’ve got some delicious specials lined up for you tonight!

🍗 WING NIGHT – Your favorite wings are back! Available for DINE-IN ONLY!

🧀 APPETIZER SPECIAL – CHEESE CURDS
Golden, crispy, and fried to perfection! The perfect way to start your meal!

🍤 SEAFOOD SCAMPI
A delicious combination of tender shrimp and scallops tossed in a rich, buttery garlic scampi sauce. Served with garlic bread and a fresh side salad!

🐔 EL CAMINO CHICKEN SANDWICH
Your choice of grilled or fried chicken, topped with our special El Camino sauce for a bold kick of flavor! Served with your choice of one side.

🍽️ Great food, cold drinks, and good company — that’s what Tuesday nights are all about!

📍 Main Street Grille | Downtown Walterboro
🕓 Doors open at 4 PM!

Come see us tonight! 🍻

It’s wing night at Main Street Grille!! Come see us!!
10/06/2026

It’s wing night at Main Street Grille!! Come see us!!

Come see us tonight!!
09/29/2026

Come see us tonight!!

THIRSTY THURSDAY !Start things off with one of our crowd-favorite appetizers:🧀 Wisconsin Cheese Curds — golden, crispy, ...
09/24/2026

THIRSTY THURSDAY !

Start things off with one of our crowd-favorite appetizers:

🧀 Wisconsin Cheese Curds — golden, crispy, and perfect for sharing!

🍄 Fried Mushrooms — fresh mushrooms, hand-breaded and fried until golden brown!

🍯🧄 HONEY GARLIC SALMON
Grilled salmon finished with a sweet and savory honey garlic sauce, served with your choice of one side and a fresh salad.

🥐🍔 THE HIGHWAYMAN!!!!!
Our signature puff pastry burger topped with homemade ranch….a Main Street Grille favorite!

🍺 Full bar, cold drinks, and the full menu available all night!

Come hungry and join us tonight at Main Street Grille!

Address

256 E Washington Street
Walterboro, SC
29488

Opening Hours

Tuesday 4pm - 11pm
Wednesday 4pm - 11pm
Thursday 4pm - 11pm
Friday 4pm - 10pm

Telephone

+18437824774

Website

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